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Scientist - Ensemble Structural Informatics (CURRENTLY NOT ACCEPTING APPLICATIONS)

Astera Institute· Radial
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Emeryville HQ$100k - $180kFull-timePosted 7mo ago

About the role

Scientist to develop standards and infrastructure for depositing, validating, searching, and leveraging dynamic structural biology data. Focus on ensemble and multistate models, cross-modality validation, and scalable databases within Prism (Radial, Astera Institute). In-person, full-time role in Emeryville, CA.

Responsibilities

  • Oversee development of ensemble-aware validation frameworks that assess fit-to-data, physical realism, and uncertainty across diverse structural representations
  • Identify and prioritize technical challenges, from data representation to validation frameworks
  • Guide the creation of data deposition, search, and retrieval tools that allow users to interrogate and interpret structural heterogeneity at scale
  • Help coordinate with stakeholders to ensure interoperability and adoption
  • Work with software developers, data engineers, and user experience designers to translate scientific requirements into robust technical solutions

Qualifications

  • Ph.D. in structural biology, biophysics, computational biology, or related field
  • Demonstrated expertise in structural biology methods
  • Deep understanding of structural heterogeneity and dynamics in biomolecular systems
  • Experience with data standards, metadata frameworks, or scientific database development
  • Strong collaborative skills and ability to build consensus across diverse scientific communities

Skills

Required:Ensemble and multistate validation designData deposition, search, and retrieval tool designStakeholder coordination

Benefits

  • Benefits summary (linked)
Last updated Oct 1, 2026. Interested? Apply on the company site.

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