Operations - Generalist / Business Operations
New YorkFull-timePosted 5mo ago
About the role
Valthos is an applied biological intelligence company and the Operations Generalist/Business Operations role supports day-to-day operations, fundraising, customer interactions, and building the company’s operational infrastructure. The role is hands-on, cross-functional, and involves owning projects end-to-end across finance, recruiting, people, legal, facilities, IT, and more, with potential to shape a future operating spine of the company.
Responsibilities
- Own the company's day-to-day operations: facilities, IT, office management, vendor management, travel, and anything else required to keep the team productive
- Build the financial backbone of the company: construct and maintain financial models, scenario-plan budget and runway, partner with external accounting on close, and run spend, payroll, and treasury as needed
- Stand up core business infrastructure, including equity administration, benefits, payroll, corporate policies, compliance, and vendor systems, choosing tools pragmatically and replacing them when we outgrow them
- Support recruiting and people operations end-to-end: source candidates, run scheduling, manage offers and onboarding, and help architect the culture and operating cadence of the company
- Lead special projects that do not fit neatly into anyone else's job description, from standing up security and clearance workflows, to opening a new office, to running internal offsites and all-hands
- Provide operational support to commercial and government engagements as needed, helping the team move proposals, contracts, and procurement workflows across the finish line
- Serve as the operational face of Valthos with external partners (investors, regulators, contractors, and vendors), and represent the company with the same bar of care as a founder would
- Close the feedback loop between the team and our partners: translate what you learn from investors, customers, and vendors into the decisions and priorities that shape how we run
Qualifications
- 3+ years in a high-ownership, high-tempo operational role, such as early-stage startup operator, chief of staff, investment banking, management consulting, private equity, or venture capital
- Demonstrated ability to own projects end-to-end in ambiguous environments, with minimal structure and minimal supervision
- Strong financial and analytical fluency; comfortable building models in Excel, running scenario analyses, and reasoning from numbers under time pressure
- Exceptional written and verbal communication. You will draft memos, investor updates, and internal and external materials that need to meet the bar of the most senior people in the room
- High attention to detail and organization. You are the kind of person who makes sure the details no one else is tracking are handled
- High ownership and a bias to action. You would rather unblock the team by fixing something yourself than wait for someone else to do it
- Comfort operating across extremes: one hour on the floor of the office, the next with a senior government stakeholder or a top-tier investor
- Willingness to travel when needed, including to customer sites
Skills
Required:Operational leadershipFinancial modelingExecutive communicationOperations and vendor managementCross-functional collaboration
Last updated Aug 5, 2026. Interested? Apply on the company site.
About Valthos
Valthos builds next-generation biodefense.
Valthos is an applied biological intelligence company. We develop and deploy software and AI methods to outsmart biological evolution and ensure that these tools are deployed to safeguard humanity.
federalbiosecuritycomputational biologybiological securityartificial intelligenceAIdefensebiology
More open roles at Valthos
- Member of Technical Staff - Design Engineer2mo agoNew York, San Francisco · Engineering
- Member of Technical Staff - Applied Computational Biologist2mo agoNew York, San Francisco · Engineering
- Operations - Growth Operations5mo agoNew York · Operations
- Member of Technical Staff - Forward Deployed Engineer6mo agoNew York, San Francisco · Engineering
- Member of Technical Staff - Software Engineer11mo agoNew York, San Francisco · Engineering