← All roles

Optical Engineer, Precision Instrumentation

Apply on company site
AlamedaFull-timePosted 2mo ago

About the role

Design and build precision optical instruments for two-photon imaging and optogenetics in neuroscience, including development of a miniature two-photon microscope and end-to-end ownership of complex instruments from concept to operation.

Responsibilities

  • Design precision optical systems for neuroscience experiments, such as large field-of-view, high-speed two-photon imaging and photostimulation microscopes.
  • Develop an advanced miniature two-photon microscope capable of simultaneous imaging and photostimulation in freely moving animals.
  • Build electronics, control hardware, and software that interface the optical systems with data acquisition and the rest of the research stack.

Qualifications

  • PhD, MS, or BS with 3-12 years of experience in optical engineering, biomedical engineering, physics, or a related field.
  • World-class generalist with hands-on experience in building precision hardware in high-precision industries (medical devices, robotics, aerospace, semiconductor capital equipment, or scientific instrumentation).
  • Experience designing and building hardware that others rely on for real work and keeping it running.
  • Resourcefulness in rapidly producing parts (machining, 3D printing, outsourcing as needed).
  • Comfort iterating from rough ideas to working instruments with collaborators.
  • Deep fundamentals in optical design and fabrication.
  • Intellectual curiosity, collaborative mindset, and willingness to learn the science around them.
  • Track record of owning complex instruments end-to-end (concept through fabrication, integration, operation).
  • Experience making and defending design tradeoffs across performance, manufacturability, cost, and timeline.
  • Experience equipping and running an optical workshop, makerspace, or prototyping facility.

Skills

Required:Optical design and fabricationInstrument end-to-end ownershipMechanical design and fabricationElectronics and control systems
Nice to have:Two-photon imaging and photostimulationCAD/CAM and 3D printing

Benefits

  • comprehensive benefits package
  • total compensation competitive and commensurate with experience and qualifications
  • equal opportunity employer, value diversity and inclusion
Last updated Sep 23, 2026. Interested? Apply on the company site.

About Astera Institute

The future, faster.

We empower visionary, high-leverage science and technology projects with the capacity to create transformative progress for human civilization.

ScienceTechnologyResearchAIOpen ScienceInnovation

More open roles at Astera Institute