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Staff Scientist, Molecular Diagnostics R&D

CareDx· RESEARCH & DEVELOPMENT
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Brisbane, CA$161k - $201kFull-timePosted 1mo ago

About the role

Lead sustaining, improvement, and product development efforts for transplant diagnostic assays in CareDx’s CLIA laboratory. Serve as technical lead on cross-functional R&D programs to drive product improvements and innovative development in gene expression profiling and low input genomics within a regulated diagnostic environment.

Responsibilities

  • Provide technical leadership for cross-functional programs, translating product needs into technical requirements and performance criteria
  • Lead assay optimization, troubleshooting, and sustaining improvements to ensure performance, robustness, and scalability of complex molecular diagnostic assays
  • Drive new product development, including experimental design, development, and analytical validation
  • Define and execute plans to validate assay performance in accordance with CLSI guidelines
  • Manage and mentor junior scientific personnel while ensuring high-quality data generation, analysis, and reporting
  • Partner cross-functionally (Bioinformatics, Clinical, Regulatory, Operations) to define development strategy and enable technology transfer

Qualifications

  • PhD in Molecular Biology, Immunology, Genomics, or related field, with 8+ years in molecular diagnostic assay development
  • Deep expertise and hands on experience with gene expression profiling, nucleic acid extraction methods, low input nucleic acid assays, NGS workflows, and PCR/qPCR
  • Strong experience with assay development, optimization, and validation in regulated environments (CLIA/CAP/FDA/ISO)
  • Proven ability to lead projects, solve complex technical problems, and collaborate across functions
  • Demonstrated experience leading small teams, including setting priorities, guiding experimental design, mentoring team members and fostering a high performance and collaborative team culture
  • Excellent communication, data analysis, and documentation skills

Skills

Required:Gene expression profilingNucleic acid extractionLow input nucleic acid assaysNGS workflowsPCR/qPCRRegulated environment validation

Benefits

  • Competitive base salary and incentive compensation
  • Health and welfare benefits, including a gym reimbursement program
  • 401(k) savings plan match
  • Employee Stock Purchase Plan
  • Pre-tax commuter benefits
  • Living Donor Employee Recovery Policy: up to 30 days paid leave annually for organ/bone marrow donation
  • Detailed benefits information available at care dx careers page
Last updated Sep 30, 2026. Interested? Apply on the company site.
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About CareDx

Together in Transplant

CareDx delivers transplant-focused diagnostics, digital health tools, and services that support patients and clinicians across the entire transplant journey.

DiagnosticsDigital HealthTransplant
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