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Founding Machine Learning Engineer

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Hybrid (San Francisco, CA)$150k - $250k + equityFull-timePosted 7mo ago

About the role

The Founding Machine Learning Engineer will build the AI systems powering the Novaflow platform, turning natural language biology queries into reliable bioinformatics workflows. This is a high-ownership, high-AGENCY role working directly with the founders to define AI strategy. In-person in San Francisco.

Responsibilities

  • ,
  • Build and improve the LLM-powered pipelines that turn natural language into bioinformatics workflows
  • - Design evaluation pipelines and benchmarks to measure model quality against real scientific expectations
  • - Experiment with fine-tuning, RAG, prompt engineering, and different model architectures
  • - Deploy and scale models in production on AWS or GCP
  • - Make build-vs-buy decisions on AI tooling and infrastructure
  • - Work across the team to integrate ML capabilities into the product

Qualifications

  • Bachelor's or Master's in Computer Science, Machine Learning, AI, or a related field (PhD is a plus)
  • 2+ years building and deploying ML models in production
  • Strong Python skills and hands-on experience with PyTorch, TensorFlow, or similar
  • Real experience with LLMs: fine-tuning, RAG, prompt engineering, evals
  • Experience working with large datasets and building data pipelines
  • Familiar with AWS or GCP for model training and deployment
  • Docker and CI/CD experience for ML workflows
  • Can spot when an LLM is confidently wrong

Skills

Required:Bachelor's or Master's in CS/ML/AIProduction ML modelingPythonPyTorch / TensorFlowLLMs (fine-tuning, RAG, prompt engineering)Data pipelinesAWS / GCPDocker / CI/CD

Benefits

  • Competitive salary and meaningful equity as a founding team member
  • 401(k) with company match
  • Unlimited PTO + federal holidays
  • Monthly health and wellness stipend
  • Meals covered when you're in the office (lunch daily, dinner when you're working late)
  • Team offsites and company events
  • Front-row seat to founder-level product strategy, customer conversations, and fundraising as we scale.
Last updated Sep 16, 2026. Interested? Apply on the company site.
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About Novaflow

The AI data analyst for biology labs

Novaflow is the AI data analyst for biology labs. -- Bioinformatics data analysis is a time-consuming and expensive process for scientists. With Novaflow, life scientists can upload experimental data, ask questions in plain English, and get instant, publication-ready plots, giving them results in minutes instead of months. In just 7 weeks, we have acquired customers at 9 institutions including UCSF, Mount Sinai, UC Berkeley, and Harvard.

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