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Pasadena, CA$90k - $165kFull-timePosted 4mo ago

About the role

Protein engineer role at Melody, a nonprofit startup focused on engineering continuous molecular monitoring technology and designing closed-loop interventions for human health. Role involves creating biosensors, guiding wet lab screening, collaborating with hardware, mentoring junior scientists, and working with academic collaborators and CRO partners.

Responsibilities

  • Design and engineer new biosensors composed of allosteric switches, signal transduction motifs (e.g., linkers), reporter proteins, site-specific chemical modifications, and bioelectronic interfaces.
  • Design new constructs and guide wet lab screening.
  • Collaborate with the hardware team to select performant constructs.
  • Mentor and manage junior scientists.
  • Collaborate with Melody’s outside academic collaborators and CRO partners.

Qualifications

  • PhD in a relevant science and engineering field with demonstrated strong independent ideation and execution or BS/MS with extensive industry experience (> 5 years).
  • Structural biology and biophysics competency related to optical and electrophysiological measurements.
  • Strength in experimental-first or computation-first track as described (self-identified).
  • Quantitative judgment for designing experiments under real-world constraints, aligning roadmap goals with instrument capabilities and throughput.
  • Demonstrated precision in experimental work and scientific project management.
  • Strong technical communication skills across relevant scientific fields and teams.

Skills

Required:Protein design and optimizationStructural biology and biophysicsExperimental methods and project managementTechnical communication
Nice to have:Data analysis scripting

Benefits

  • 401k match up to 6% of base salary.
  • Excellent health, vision, and dental benefits.
  • Paid time off and company holidays.
Last updated Oct 21, 2026. Interested? Apply on the company site.

About Convergent Research

A mission control for frontier technology

A mission control for frontier technology

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