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Founding Engineer

Astraea· Engineering
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Hybrid (San Francisco, CA)$150k - $300kFull-timePosted 3mo ago

About the role

Founding engineer role at Astraea, building deeply technical AI systems for regulated clinical development, with ownership across frontend, backend, data infrastructure, and AI orchestration.

Responsibilities

  • Build agentic workflows for clinical trial automation
  • Design reliable systems for document ingestion, data transformation, validation, and auditability
  • Own core product surfaces across frontend, backend, data infrastructure, and AI orchestration
  • Work closely with clinical teams to turn messy real-world workflows into production software
  • Ship quickly while maintaining rigor required for regulated healthcare environments

Qualifications

  • An exceptional full-stack or backend engineer
  • Experience integrating AI into production systems, including legacy environments (preferred)
  • Ability to move fast, take ownership, and problem-solve in ambiguity
  • Interest in using AI to automate healthcare, clinical trials, or regulated data workflows
  • Willingness to join at the earliest stage and help define engineering culture

Skills

Required:ReactTypeScriptPrompt EngineeringAI Agents
Nice to have:LangChain

Benefits

  • Not specified in description
Last updated Oct 25, 2026. Interested? Apply on the company site.
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About Astraea

AI Operating System for Clinical Development

Astraea automates clinical trial biometrics from raw study inputs to FDA-ready outputs. The platform handles data normalization, CDISC mapping, SDTM, ADaM, TFLs, QC, and revision workflows in one auditable system, helping Phase II/III sponsors reduce months of manual programming and data management into automated, reviewable execution.

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