Clinical Expert, Onco-Immunology
Bioptimus· Research & Technology
Hybrid (Paris (HQ) / Remote EU)part-timePosted 3mo ago
About the role
Clinical Expert to support Bioptimus’s clinical and scientific strategy for digital twin and data generation programs, contributing clinical prioritization, interpretation of model outputs, and partnerships across research programs. Part-time with possibility to become full-time. Remote-friendly (EU/Paris HQ).
Responsibilities
- Clinical Strategy: Support identification of important clinical questions and modalities to prioritize across training and validation cohorts. Provide clinical input on tissue, drug class, disease, and modality prioritization. Support selection of clinical metadata, endpoints, and patient-level annotations to maximize downstream model utility. Identify and prioritize clinically relevant tasks including response prediction, toxicity prediction, biomarker discovery, indication expansion, and trial enrichment.
- Scientific Interpretation: Provide clinical and biological review of model outputs and scientific results. Work with science team to review results and contribute to external-facing scientific narratives. Translate model behavior into clinically credible language for pharmaceutical, KOLs, and regulatory audiences.
- Data & Academic Partnerships: Support connections with academic investigators running relevant clinical studies, including early-phase studies, novel-agent programs, immuno-oncology programs, and multimodal cohorts. Advise on partnership structures aligning research collaborations with Bioptimus’ data needs, including retrospective and prospective studies.
- Pharma Engagement: Support discussions with pharmaceutical R&D teams. Advise on positioning of model claims for translational medicine and clinical development audiences.
Qualifications
- MD/PhD with active or recent Principal Investigator experience designing and analyzing clinical studies, particularly studies involving translational endpoints, biomarker sub-studies, and multimodal cohorts.
- Deep expertise in onco-immunology, including IO mechanisms, response and resistance biology, tumor microenvironment biology, IO combinations, and understanding of pharmaceutical pipelines and unmet clinical needs.
- Working understanding of and genuine interest in machine learning and foundation model approaches applied to pathology, transcriptomics, and multimodal data integration.
- Ability to work closely with scientific, clinical, and external stakeholder groups. Strong communication skills with the ability to contribute to scientific discussions and external-facing narratives. Comfortable operating in a startup environment with ambiguity and evolving priorities.
Skills
Required:Clinical Research ExperienceOnco-Immunology ExpertiseMachine Learning & multimodal biologyCollaboration & Communication
Benefits
- Remote work option
- Opportunity to influence translational medicine strategy in a cutting-edge AI-biotech startup
- Collaborative, innovation-driven environment with top researchers and industry experts
Last updated Oct 14, 2026. Interested? Apply on the company site.
About Bioptimus
Bioptimus | Building the world model of biology
Building the world model of biology.
AI in biologyBiologyDiagnostics & spatial biologyDrug target & biomarker discoveryGenomicsH-OptimusIndication expansionM-Optimus
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