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Process Engineer, Isotopes

Oklo· Engineering
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Hybrid (Santa Clara, CA or Remote)$130k - $200kFull-timePosted 2mo ago

About the role

Process Engineer to design, analyze, and operate fluid and power process systems for isotope production, recovery, purification, and handling within Oklo’s Isotopes team. Emphasis on safe, reliable, and scalable production processes.

Responsibilities

  • Design fluid and process systems including: piping, valves, compressors, pumps, and heat exchangers for isotope production, recovery, purification, and supporting process systems
  • Define process equipment architecture, specifications, operational modes, and performance criteria
  • Design, assemble, and operate prototypes to use for iterative design refinement, including bench-scale or pilot-scale process demonstrations
  • Generate documentation guiding the system layout, fabrication, installation, commissioning, operation, and maintenance of process equipment with consideration for contamination control, radiological controls, and safe operation
  • Serve as process system owner for assigned systems, maintaining their design basis, configuration, and performance throughout the lifecycle
  • Prepare technical documentation supporting regulatory filings, safety analyses, and isotope production operations
  • Work with external vendors on process equipment analysis, procurement, and testing
  • Develop and maintain process flow diagrams, piping and instrumentation diagrams, mass and energy balances, equipment specifications, and operating envelopes for isotope production systems
  • Support isotope product requirements, including yield, purity, traceability, and contamination limits
  • Conduct process hazard analyses and implement risk reduction measures addressing equipment and process failure modes, chemical hazards, criticality interfaces, radiological hazards, and abnormal operating conditions

Qualifications

  • Bachelor's degree in mechanical, chemical, nuclear, radiological, materials, aerospace, petroleum, or a related engineering discipline
  • 5+ years of experience designing, analyzing, or modifying fluid, thermal, or process systems and equipment in nuclear, radiopharmaceutical, isotope production, or related industries
  • Strong understanding of engineering fundamentals, systems design and integration, equipment interfaces, and process system operation
  • Ability to apply process engineering fundamentals to systems involving radioactive materials, chemical separations, gas/liquid handling, thermal management, contamination control, and product quality requirements

Skills

Required:Process design and analysisRegulatory documentation and safety analysesPrototyping and testingProcess hazard analysis
Nice to have:Vendor engagement

Benefits

  • flexible time off
  • equity
  • bonuses
  • competitive pay
  • 401(k)
  • health insurance (with employer contribution)
  • HSA
  • FSA
  • flexible work hours
  • wellness credits
  • other benefits
Last updated Aug 21, 2026. Interested? Apply on the company site.
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About Oklo

Emission free, always on power from advanced fission power plants.

About Oklo Inc.: Oklo Inc. (Oklo) is developing advanced fission power plants to provide emission-free, reliable, and affordable energy. Oklo received a Site Use Permit from the U.S Department of Energy, has performed successful prototypic fuel fabrication, was awarded fuel material from Idaho National Laboratory, developed the first advanced fission combined license application accepted and docketed by the U.S. Nuclear Regulatory Commission, and is developing advanced fuel recycling technologies in collaboration with the U.S. Department of Energy and national laboratories. Oklo has been featured in Time, Newsweek, Wall Street Journal, CNBC, Popular Mechanics, Wired, Architectural Digest, Hyperallergic, POWER Magazine, has been the subject of a Harvard Business School case, and is featured in the Oliver Stone documentary Nuclear, among other features.

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