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Principal/Director, Product Management

Heartflow· Product Management
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San Francisco, CA$240k - $295kFull-timePosted 1mo ago

About the role

Senior individual-contributor product leader responsible for strategy and execution of a portfolio of medical-grade products in Heartflow’s FDA-regulated environment, focusing on clinical workflow, validation, regulatory strategy, and cross-functional alignment to deliver impactful cardiovascular care solutions.

Responsibilities

  • Product strategy: Own the multi-year portfolio strategy, define problems worth solving, sequence bets, and drive decisions on build/partner/acquire options.
  • Performance and outcomes: Define shipped criteria, performance targets, failure modes, and patient-population boundaries; own claims strategy with Clinical and Regulatory.
  • Care-pathway ownership: Map product integration across referral, acquisition, interpretation, reporting, follow-up, and reimbursement.
  • Requirements and design authority: Author user needs and system requirements; resolve contested requirements across functions.
  • Regulatory and evidence strategy: Lead FDA interactions, pre-submission strategy, V&V planning, study design, post-market surveillance; maintain design history and TRACEABILITY.
  • Cross-functional influence: Align engineering, data science, UX, human factors, clinical, QA/RA, marketing, and support around a single product intent without formal authority.
  • Customer and market engagement: Maintain relationships with physicians, key opinion leaders, advisors, and health-system customers; bring competitive and literature insights to roadmap.
  • Executive communication: Provide leadership with quantified portfolio risk, performance, and progress.

Qualifications

  • Extensive product management experience with FDA-regulated software, including at least one product from concept through clearance/approval to routine use.
  • Real depth in cardiovascular disease, diagnostic imaging/interpretation, multimodal risk assessment, disease pathogenesis, or decision support.
  • Fluency in validation of medical products: study/dataset design, generalization across populations/sites, sensitivity/specificity trade-offs, real-world performance vs benchmark.

Skills

Required:Product strategyRegulatory strategyData-driven decision makingCross-functional leadership without formal authorityClinical workflow understanding
Last updated Sep 14, 2026. Interested? Apply on the company site.

About Heartflow

Decisive Coronary Care

Heartflow’s vision is to transform CAD from the leading cause of death into a disease that can be managed for life.

CCTA ResourcesRoadmap AnalysisFFRCT AnalysisPlaque AnalysisHeartflow OneHeartflow One PlatformMeasurable Impact
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