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Senior Scientist / Scientist, In Vivo Pharmacology

NewLimit· Metabolism
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South San Francisco, CA$130k - $180kfull-timePosted 1w ago

About the role

Senior Scientist/Scientist in In Vivo Pharmacology to design and execute in vivo studies evaluating epigenetic reprogramming therapeutics, lead study design and CRO/vendor management, and drive preclinical decision making.

Responsibilities

  • Design, execute, and interpret in vivo pharmacology studies (PK/PD, efficacy, dose-response) across multiple disease models and therapeutic programs
  • Collaborate with Epigenetic Editing, Predictive Modeling, and other therapeutic area teams to evaluate epigenetic reprogramming payloads in relevant animal models
  • Develop and refine animal models of aging and age-related disease to support translational studies
  • Oversee study design, protocol development, and CRO/vendor relationships for in vivo studies
  • Analyze and interpret in vivo data (PK/PD, biomarkers, functional endpoints) to drive pre-clinical decision making
  • Contribute to regulatory-enabling study design and documentation as programs progress toward clinical

Qualifications

  • Ph.D. in pharmacology, physiology, biology or a related field or equivalent industry experience (5+ years for Scientist; 8+ years for Senior Scientist)
  • Demonstrated experience designing and executing in vivo pharmacology studies (PK, PD, efficacy, dose-range finding) in rodent models
  • Experience with study design, dosing regimens, and route-of-administration selection
  • Experience analyzing and interpreting in vivo pharmacology data to inform program decisions
  • Experience leading project workflows and providing technical mentorship to junior laboratory staff
  • History of contributing to a drug development program at the pre-clinical or clinical development stage

Skills

Nice to have:In vivo pharmacology study design

Benefits

  • Health, dental, and vision insurance
  • 401(k) with company match
  • Paid parental leave
  • Industry-leading paid time off (PTO) — 20 days/year for all employees + holidays
  • Meals and snacks on-site
Last updated Sep 10, 2026. Interested? Apply on the company site.

About NewLimit

Extending human healthspan

NewLimit is extending human healthspan by unlocking regenerative potential.

reprogrammingepigeneticsmedicineaginglongevity
Company profileWebsite

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