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Staff IT Systems Engineer, Endpoints

Lila Sciences· Business Operations
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Cambridge, MA$140k - $186.7kfull-timePosted 4d ago

About the role

Own the architecture and roadmap for endpoint management across the company, treating endpoint management as a software engineering discipline with code-driven configuration, rollout, and observability. Lead cross-functional initiatives, mentor engineers, and build tooling to automate and secure endpoints across macOS, Windows, Linux, mobile, and specialized research compute.

Responsibilities

  • Own the architecture and roadmap for Lila’s endpoint fleet across macOS, Windows, Linux, mobile devices, and specialized research or lab computing endpoints.
  • Define standards for endpoint configuration, policy, remediation, observability, and rollout practices across the IT & Security team.
  • Drive configuration-as-code adoption for MDM policies, profiles, scripts, staged rollouts, canary groups, and automated rollback.
  • Design zero-touch provisioning workflows so devices arrive encrypted, configured, compliant, and productive out of the box.
  • Partner with Security to integrate endpoint posture, device trust, vulnerability data, EDR, and Zero Trust access controls.
  • Build automation and internal tooling using scripts, APIs, CI/CD, and AI-assisted engineering practices to reduce manual toil.
  • Improve vulnerability and patch management through telemetry, dashboards, drift detection, and auditable compliance workflows.
  • Support specialized computing environments, including research workstations, lab-adjacent systems, VDI, managed browsers, and remote-access patterns where appropriate.
  • Serve as a technical escalation point for complex endpoint issues and mentor engineers across IT and Security.
  • Partner across Security, Legal, HR, Research Computing, and Lab Operations to protect sensitive IP while keeping the employee experience seamless.

Qualifications

  • Deep experience in IT systems engineering, endpoint engineering, infrastructure, or platform engineering, with staff-level technical ownership.
  • Strong experience with modern MDM or UEM platforms such as Jamf, Intune, Workspace ONE, or similar tools.
  • Experience managing endpoint configuration through code, automation, version control, staged rollout, or CI/CD practices.
  • Strong systems knowledge across macOS and Windows endpoint environments.
  • Ability to build and maintain automation using Python, Bash, PowerShell, APIs, or similar tooling.
  • Experience using AI-assisted engineering, LLM APIs, internal copilots, or agentic automation to reduce operational toil in IT, endpoint, infrastructure, or platform operations.
  • Experience partnering with Security on endpoint hardening, device trust, vulnerability management, EDR, or Zero Trust initiatives.
  • Strong troubleshooting ability across endpoint, identity, network, application, and user-experience boundaries.
  • Track record mentoring engineers, setting technical standards, and leading cross-functional technical initiatives.
  • Clear written and verbal communication skills with the ability to influence technical decisions across teams.

Skills

Required:Endpoint engineeringMDM/UEMAutomationCI/CDSecurity collaborationTroubleshootingMentoring

Benefits

  • Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.
Last updated Oct 21, 2026. Interested? Apply on the company site.
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About Lila Sciences

Pioneering Scientific Superintelligence

Pioneering Scientific Superintelligence to solve humankind’s greatest challenges.

Scientific SuperintelligenceAIAutonomous LabsLife SciencesChemical SciencesMaterials Sciences
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