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Antibody Engineering

Chai Discovery· Science
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San Francisco officeFull-timePosted 11mo ago

About the role

We are seeking exceptional antibody engineers and computational protein designers to evaluate, expand, and apply de novo antibody design models within Chai Discovery’s AI-powered drug discovery platform.

Responsibilities

  • Evaluate, expand and apply the capabilities of de novo antibody design models.
  • Join an elite team of biologists, computational scientists and AI researchers.
  • Probe design space for novel targets and formats, validate in silico solutions for function in the lab.
  • Execute experimental programs at scale that guide, train and evaluate next generation models.
  • Collaborate with scientists from pharma companies to push discovery programs into new territory.

Qualifications

  • PhD or equivalent experience in Antibody Engineering, Computational Biology, or Protein Sciences.
  • Hands-on experience with design and characterization of antibody-based biologics.
  • Proficient in molecular-biology workflows, binding and developability assays.
  • Ability to inspect structures in PyMOL or similar tools.
  • Track record of strong communication, collaboration and execution.

Skills

Required:Antibody design and engineeringMolecular biology workflowsBinding and developability assaysComputational biology tools (e.g., PyMOL)Communication and collaboration

Benefits

  • Competitive compensation.
  • Culture of high velocity and ownership.
  • Opportunity to work at the vanguard of AI research and frontier biology.
Last updated Oct 14, 2026. Interested? Apply on the company site.

About Chai Discovery

Building frontier artificial intelligence to predict and reprogram the interactions between biochemical molecules.

Building frontier artificial intelligence to predict and reprogram the interactions between biochemical molecules.

artificial intelligencebiochemical moleculesliquid-ai-recruiting-target

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