Senior Software Engineer, Prenatal
About the role
Senior Software Engineer to join BillionToOne’s prenatal software engineering team. Hybrid onsite 3 days/week in Menlo Park, focusing on scalable backend services, platform APIs, and cloud infrastructure to support high-volume, enterprise-grade genomic medicine delivery.
Responsibilities
- Design, build, and operate scalable, high availability backend services, APIs, and data integrations that power customer facing product experiences
- Lead technical delivery across the full lifecycle: architecture, design, implementation, testing, deployment, and ongoing operations
- Collaborate closely with product, design, and cross functional engineering teams to deliver performant, reliable, and intuitive platform capabilities
- Develop clean abstractions and platform APIs that simplify complex LIS workflows while balancing developer velocity with long term system stability
- Build and maintain secure, reliable cloud infrastructure on AWS, including compute environments, networking, container orchestration, storage, and environment automation
- Implement CI/CD pipelines, Infrastructure as Code, configuration management, and automated environment provisioning to standardize and accelerate delivery
- Embed observability and operational excellence into the platform by default through robust monitoring, logging, alerting, and reliability patterns
- Ensure the scalability, maintainability, and overall health of backend and cloud systems as the platform grows to support large enterprise workloads and future global expansion
- Foster a culture of ownership, technical excellence, learning, and continuous improvement within the engineering team
- Apply AI-assisted tooling and workflows to improve developer productivity, automate routine engineering tasks, enhance code quality, and accelerate troubleshooting
Qualifications
- 5 - 7 years of professional software development experience with a proven track record of delivering complex projects adhering to best practices
- Deep understanding and experience using web frameworks like Django and FastAPI
- Strong system design and architecture capabilities, applying domain-driven design to translate complex business domains into clear, scalable service and data boundaries.
- Familiarity with modern AI-driven development practices and tools.
- Strong foundation in cloud services, preferably AWS, including ECS, S3, AWS Batch, EC2, and AWS Lambda, enabling effective architecture and management of complex systems
- Excellent communication and collaboration skills, with the ability to work effectively in a team-oriented environment
- Excited about working in-person with our team in Menlo Park
Skills
Benefits
- Multiple medical benefit options; employee premiums paid 100% on select plans, dependents covered up to 80%
- Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
- Supplemental fertility benefits coverage
- Retirement savings program including a 4% Company match
- Increase paid time off with increased tenure
- Latest and greatest hardware (laptop, lab equipment, facilities)
- Daily on-site lunches provided from top eateries
- A variety of perks on campus (state of the art gym, restaurant)
- Free on-site EV charging (compatible with all EVs, including Tesla)
- Open, transparent culture with weekly Town Hall meetings
About BillionToOne
The genetic testing platform detecting and measuring disease.
BillionToOne has developed a DNA molecular counter that increases the cell-free DNA diagnostics resolution by over 1,000 fold, which unlocks transformative improvements in prenatal screening and liquid biopsy for cancers. Unity Screen, BillionToOne's commercially available non-invasive prenatal test (NIPT), is the only NIPT that can assess fetal risk for both recessive conditions and aneuploidies from maternal blood. UNITY Screen continues to grow exponentially and is on its path to becoming the next standard-of-care, with an increasing number of publications showing its accuracy and advantages over other screening methods. We have also recently used our molecular counting technology to develop liquid biopsy tests, which have the potential to completely transform oncology care.
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