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Senior AI Engineer I

BillionToOne· Engineering
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Hybrid (Menlo Park, CA)$174.2k - $200.6kFull-timePosted 5mo ago

About the role

Senior AI Engineer I role focused on designing and implementing AI and automation solutions to optimize operations across commercial, billing, and customer experience teams. Hybrid in-person role in Menlo Park, CA.

Responsibilities

  • Build and deploy LLM-powered applications (retrieval systems, AI agents, workflow automation, vector storage) that integrate with internal systems and data sources
  • Partner with business stakeholders to identify automation opportunities, scope requirements, and define success metrics
  • Build lightweight data pipelines and analytics to support AI applications and measure their impact
  • Own projects end-to-end: from prototyping and iteration through production deployment and monitoring
  • Establish best practices for prompt engineering, evaluation, and responsible AI use as the team scales
  • Develop and lead internal training sessions on LLM fundamentals, prompt engineering, and AI-assisted development tools

Qualifications

  • 5+ years of experience in software engineering, data science, or ML engineering
  • Hands-on experience building applications with LLM APIs (OpenAI, Anthropic, etc.)
  • Strong Python proficiency and comfort with SQL and relational databases
  • Experience deploying and maintaining production systems
  • Familiarity with AWS
  • Excellent communication skills and ability to translate business problems into technical solutions
  • Self-directed and comfortable with ambiguity in a 0-to-1 environment

Skills

Required:PythonSQLLLM APIsProduction systems
Nice to have:AWS

Benefits

  • Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
  • Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
  • Supplemental fertility benefits coverage
  • Retirement savings program including a 4% Company match
  • Increase paid time off with increased tenure
  • Latest and greatest hardware (laptop, lab equipment, facilities)
  • Daily on-site lunches provided from top eateries
  • A variety of campus perks (gym, restaurant)
  • Free on-site EV charging (compatible with all EVs, including Tesla)
  • Open, transparent culture with weekly Town Hall meetings
  • Base pay range and equity options with bonus program; total compensation package advertised at $280,705/year (base $174,241 - $200,641)
Last updated Oct 7, 2026. Interested? Apply on the company site.
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About BillionToOne

The genetic testing platform detecting and measuring disease.

BillionToOne has developed a DNA molecular counter that increases the cell-free DNA diagnostics resolution by over 1,000 fold, which unlocks transformative improvements in prenatal screening and liquid biopsy for cancers. Unity Screen, BillionToOne's commercially available non-invasive prenatal test (NIPT), is the only NIPT that can assess fetal risk for both recessive conditions and aneuploidies from maternal blood. UNITY Screen continues to grow exponentially and is on its path to becoming the next standard-of-care, with an increasing number of publications showing its accuracy and advantages over other screening methods. We have also recently used our molecular counting technology to develop liquid biopsy tests, which have the potential to completely transform oncology care.

diagnosticsgenomics

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