Founding Bioinformatics Engineer
About the role
Founding Bioinformatics Engineer at Novaflow, a fast-growing YC-backed startup building AI-powered bioinformatics analytics for biology labs. Owns the analysis pipelines, ensures scientific validity, and scales workflows on cloud infrastructure. High-ownership, high-agency role in-person in San Francisco working directly with the founders.
Responsibilities
- Build and maintain bioinformatics pipelines for genomics, transcriptomics, and other -omics data
- Write clean, reproducible analysis code in Python and/or R
- Set up and manage cloud infrastructure (AWS or GCP) for large-scale compute workloads
- Integrate existing bioinformatics tools, databases, and data sources into the platform
- Validate pipeline outputs against published methodologies and real scientific standards
- Work with academic labs, tool providers, and data partners to expand what the platform can do
- Help decide what we build next based on what researchers actually need
Qualifications
- Bachelor's or Master's in Computational Biology, Bioinformatics, Biomedical Engineering, or a related field (PhD is a plus)
- 2+ years building bioinformatics pipelines or computational biology workflows
- Strong in Python and/or R
- Know your way around bioinformatics file formats (FASTQ, BAM, VCF, HDF5, etc.)
- Experience running workloads on AWS or GCP
- Comfortable in Linux/Unix command-line environments
- Solid understanding of molecular biology (genomics, gene expression, variant calling)
- Good communicator who can work across biology and engineering
Skills
Benefits
- Competitive salary and meaningful equity as a founding team member
- 401(k) with company match
- Unlimited PTO + federal holidays
- Monthly health and wellness stipend
- Meals covered when you're in the office (lunch daily, dinner when you're working late)
- Team offsites and company events
- Front-row seat to being a founder with visibility into product strategy, customer conversations, and fundraising as we scale.

About Novaflow
The AI data analyst for biology labs
Novaflow is the AI data analyst for biology labs. -- Bioinformatics data analysis is a time-consuming and expensive process for scientists. With Novaflow, life scientists can upload experimental data, ask questions in plain English, and get instant, publication-ready plots, giving them results in minutes instead of months. In just 7 weeks, we have acquired customers at 9 institutions including UCSF, Mount Sinai, UC Berkeley, and Harvard.
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