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Senior Manager / Director, Statistical Genetics

insitro· Data Science and Machine Learning
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South San Francisco, CA$224k - $273kFull-timePosted 4w ago

About the role

Lead and grow a team of statistical geneticists to advance insitro's machine learning statistical genetics platform, extract novel biological insights from human genetics, and translate findings into therapeutic programs.

Responsibilities

  • Lead, mentor, and grow a team of four statistical geneticists developing methods to extract insight from human genetics
  • Define the roadmap and priorities for statistical genetics at insitro, and uphold rigor
  • Lead the team in building new ML methodology that extracts more signal from human genetics and integrates it with other data modalities
  • Partner with software engineering to turn one-off analyses into well-tested workflows for the research organization
  • Own GWAS, rare variant, and post-GWAS analyses across internal indications to identify and prioritize novel targets, moving from association to causal hypothesis
  • Partner with therapeutic area and drug discovery scientists to convert genetic findings into validated, tractable programs

Qualifications

  • PhD in statistical genetics, human genetics, computational biology, biostatistics, or related field, plus 5+ years of experience
  • Deep knowledge of statistical genetics as applied to target discovery in an industry setting
  • Direct people management experience, with a track record of mentoring and growing technical talent
  • Demonstrated experience applying machine learning to genetic, imaging, or other clinical data
  • History of publication and methodological innovation in statistical genetics
  • Clear and collaborative cross-functional communication across experimental scientists and software engineers

Skills

Required:Team leadership and mentorshipStatistical geneticsMachine learning in genetics

Benefits

  • 401(k) plan with employer matching
  • Excellent medical, dental, and vision coverage as well as mental health and well-being support
  • Open, flexible vacation policy
  • Paid parental leave of at least 16 weeks to support birth or adoption events
  • Quarterly budget for books and online courses for self-development
  • New hire stipend for home office setup
  • Monthly cell phone & internet stipend
  • Free onsite baristas and daily lunch for onsite/hybrid employees
  • Free commuter bus network to South San Francisco HQ
Last updated Sep 24, 2026. Interested? Apply on the company site.

About insitro

Making Medicines Differently

At insitro, we are building a different kind of drug company to bring better drugs faster to the patients who can benefit most. Through the power of machine learning (ML) and data at scale, we decode the complexities of biology to unlock transformative new medicines.

PipelinePlatformPeoplePublications & PressML-driven platformdrug discoveryneurosciencemetabolism

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