Engineer I, Research Operations, (1st shift)
Cambridge, MA$75.6k - $100.8kfull-timePosted 2w ago
About the role
Engineer I to support mammalian cell-based workflows (electroporation, LNP dosing, chemical transfection) in a first-shift, on-site role, combining hands-on cell culture with laboratory automation to deliver high-quality materials and improve workflow reliability and traceability.
Responsibilities
- Execute high-throughput automated and manual workflows, including electroporation, lipid nanoparticle (LNP) dosing, and chemical transfection.
- Maintain and passage mammalian cell lines and primary cells using aseptic technique, including cell counting and viability assessment.
- Prepare workflow materials and operate automated liquid handlers, electroporation instruments, and related laboratory equipment.
- Perform downstream characterization using flow cytometry, plate reader-based assays, or imaging-based methods.
- Monitor cell health, workflow performance, and quality-control results; troubleshoot issues and escalate as needed.
- Maintain traceable records, provide clear handoffs, and partner with scientists and engineers to improve standard operating procedures (SOPs) and workflows.
Qualifications
- Bachelor’s degree in Biology, Biotechnology, Biochemistry, Cell Biology, Bioengineering, or a related scientific or engineering field, or an equivalent combination of education and relevant laboratory experience.
- Minimum 3 years of relevant Co-Op and industry laboratory experience.
- Hands-on mammalian cell culture experience, including aseptic technique, routine maintenance, passaging, cell counting, and viability assessment.
- Experience with mammalian cell transfection methods, including chemical transfection, electroporation, or related delivery technologies.
- Strong attention to detail and ability to follow SOPs and technical instructions while maintaining accurate, complete, and traceable documentation.
- Strong analytical and problem-solving skills, including recognizing deviations, performing initial troubleshooting, and escalating appropriately.
- demonstrated ability to manage multiple priorities and execute reliably in a fast-paced, high-throughput laboratory environment.
- Strong communication and collaboration skills, with the ability to provide clear status updates and work effectively across teams.
- Ability to work on-site during first shift, with scheduled hours of either 7:00 AM to 3:00 PM or 9:00 AM to 5:00 PM based on operational needs.
Skills
Required:Mammalian cell cultureTransfection methodsAutomation & instrumentationDocumentation & SOPsCommunication & collaboration
Benefits
- Full-time U.S. benefits including medical, dental, and vision; employer-paid life and disability insurance; flexible time off with holidays; paid parental leave; educational assistance; commuter benefits (bike share); company subsidized lunch program.
- International benefits tailored to region; USD salary ranges apply to U.S.-based positions; international salaries set to local market.
Last updated Oct 7, 2026. Interested? Apply on the company site.
About Lila Sciences
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