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Flow Cytometry Systems Engineer

Nomic Bio· Engineering
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Greater Boston, MontrealFull-timePosted 4mo ago

About the role

Internal subject-matter expert for commercial flow cytometers used across operations, development, and customer deployments; supports maintenance, troubleshooting, and integration of cytometers for nELISA readout and on-site kit execution, spanning internal teams and customer deployments.

Responsibilities

  • Evaluate cytometer-related sources of variability and help implement improvements to reduce failure modes in internal and customer workflows.
  • Work with internal teams and external vendors to resolve recurring instrument or workflow issues.
  • Help establish platform-level knowledge around cytometer fluidics, optics, lasers, detectors, compensation, gating, controls, bead-based assays, and QC metrics.
  • Contribute to continuous improvement projects that make cytometry workflows more robust, transferable, and easier to operate.
  • Support the selection, qualification, and operationalization of cytometry platforms and accessories as Nomic scales.
  • Serve as internal expert for commercial flow cytometers used in internal operations, assay development, QC, and deployment workflows.
  • Support cytometer setup, daily operation, calibration, QC, maintenance, troubleshooting, and performance monitoring.
  • Maintenance and repair across the cytometer fleet, including parts replacement, fluidics, optics alignment, and deeper hardware work.
  • Help internal teams understand how cytometer performance affects assay quality, data quality, reproducibility, and operational reliability.
  • Diagnose issues across instruments, reagents, samples, acquisition settings, cytometry templates, controls, user technique, and data quality.
  • Develop and maintain SOPs, training materials, maintenance schedules, QC checklists, troubleshooting guides, and vendor escalation playbooks.
  • Improve cytometer uptime, assay robustness, workflow consistency, and operator training with operations and development teams.
  • Support deployment customers running Nomic kits on-site with their own commercial cytometers.
  • Assess customer cytometer readiness and workflow compatibility; configure instrument settings and QC procedures.
  • Support customer onboarding, protocol transfer, cytometer setup, and troubleshooting for successful kit execution.
  • Provide remote and on-site technical support during deployments.
  • Translate field learnings into documentation, training, protocols, and product requirements with cross-functional teams.
  • Build scalable support processes for reliable kit operation across different customer environments.
  • Travel (>50%) to support internal sites (Montreal, Boston) and visit customer sites as needed.
  • Evaluate sources of variability in cytometry workflows and drive improvements.
  • Resolve recurring instrument or workflow issues with internal and external teams.
  • Establish platform knowledge on cytometer components and QC metrics.
  • Contribute to continuous improvement projects for robustness and transferability.
  • Support platform and accessory selection as the company grows.

Qualifications

  • Bachelor’s degree or higher in bioengineering, mechanical engineering, biomedical engineering, biotechnology, or related engineering discipline.
  • 4+ years of industry experience in technical applications, field applications, field service, field deployment, or life science instrumentation.
  • Recent hands-on experience supporting flow cytometers, ideally in a customer-facing role.
  • Strong understanding of flow cytometry hardware and assays (setup, fluidics, optics, lasers, detectors, calibration, QC, controls, compensation, gating, data acquisition, troubleshooting).
  • Experience with commercial flow cytometry platforms from Bio-Rad, Cytek, BD, Beckman Coulter, Sony Biotechnology, Thermo Fisher, or similar.
  • Comfortable training and supporting non-expert operators through documentation and hands-on help.
  • Experience supporting customer installations, assay transfers, product deployments, instrument qualification, or on-site implementations.
  • Experience in a fast-paced startup or scaling technical operations environment.
  • Strong written and verbal communication; ability to create SOPs, technical guides, training materials, and support documentation.
  • Ability to work cross-functionally with Operations, R&D, Product, Quality, Commercial, and customer-facing teams.

Skills

Required:Flow cytometry knowledgeInstrument maintenance and repairTraining & documentationCross-functional collaboration

Benefits

  • Apply via the provided job link.
Last updated Jul 22, 2026. Interested? Apply on the company site.
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About Nomic Bio

Nomic is doing for proteins what Illumina has done for DNA

Nomic is doing for protein profiling, what Illumina did for DNA sequencing. Our core technology, the nELISA, is a next-gen immunoassay platform that transforms the ELISA into a high-throughput, high-content, and high-versatility tool. Today we developed the nELISA for high-throughput drug discovery scientists, enabling them profile 100s of proteins at 10x higher throughput and 10x lower cost compared to existing solutions. We're offering the nELISA through early access programs to HTS groups in top pharmas as well as pioneering biotechs in the space. Our goal is to create a ubiquitous technology that consolidates the broad range of legacy immunoassay toolkits that scientists use today with a single platform that can carry the science end-to-end, from discovery all the way to the clinic. We're a team of engineers, biologists, and highly-skilled lab operators that are looking to grow quickly to keep up with customer demand but also to continue developing our core technology, scale our multiplexing/throughput, and build our software stack. We're hiring on a number of positions including engineering, software, biology, and ops. Come talk to us!

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