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Associate Director of Bioinformatics (Women's Health and Organ Health)

Natera· Molecular Biology Informatics & Statistics
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San Carlos, CA$177.8k - $222.2kFull-timePosted 2mo ago

About the role

Leadership role overseeing a team of Bioinformatics Scientists in the Women’s Health and Organ Health research organization, driving research strategy, assay development, and production-ready pipeline development in a regulated (CLIA) environment.

Responsibilities

  • Lead and mentor a team of Bioinformatics Scientists. Own their professional growth, responsibilities, and standards.
  • Own the research strategy behind new product development, from scoping through execution, with cross-functional stakeholders.
  • Lead bioinformatics analysis for assay development and optimization across multi-omic approaches (methylation, fragmentomics, cfDNA features) and sequencing modalities (short-read and long-read; hybrid-capture and amplicon).
  • Partner with laboratory teams on study design at research/feasibility stage, ensuring data quality for product development.
  • Advise and prototype improvements to analysis pipelines (variant detection, QC, methylation calling, fragment-size/end-motif analysis, SCC for deep targeted panels, SV calling).
  • Move research prototypes into stable production workflows with proper software engineering practices (version control, testing, CI/CD, containerization) and automate routine data management, pipeline execution, and reporting.
  • Define appropriate use of AI tools within the team and establish standards for when human sign-off is required.
  • Collaborate with data science, molecular biology, pipeline engineering, biostatistics, QA, and lab operations; act as SME and communicate findings and roadmaps across the company.

Qualifications

  • Ph.D. in Bioinformatics, Computational Biology, Computer Science, Mathematics, Engineering, Biostatistics, or related field (M.S. with equivalent experience considered).
  • 7+ years in bioinformatics, including 3+ years leading scientists and cross-functional work.
  • Demonstrated ownership of a team that translated scientific research into real clinical use.
  • Demonstrated experience developing or scientifically guiding diagnostic sequencing assays.

Skills

Required:Next-generation sequencing analysiscfDNA / multi-omics data analysisRegulated product developmentPython programming and data analysisCommunicationProject and team leadership
Nice to have:AI tooling usage in workflows

Benefits

  • Annual performance incentive bonus
  • Long-term equity awards
  • Comprehensive health benefits (medical, dental, vision)
  • 401(k) with company match
  • Generous paid time off and company holidays
  • Additional wellness and work-life benefits
Last updated Aug 13, 2026. Interested? Apply on the company site.

About Natera

A global leader in cfDNA testing

Dedicated to oncology, women’s health, and organ health. Natera’s cell-free DNA tests help protect health and inform more personalized decisions about care.

oncologywomen's healthorgan healthcell-free DNA
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