← All roles

Supervisor, Oncology RUO

Natera· Bio Development
Apply on company site
San Carlos, CA$82.3k - $102.9kfull-timePosted 2mo ago

About the role

Supervisor for the Signatera Plasma Team within Natera’s Oncology Research Use Only (RUO) group, directing lab staff in cfDNA extraction, library preparation, and NGS workflows to support personal MRD assays.

Responsibilities

  • Oversee the daily scheduling of employees executing DNA extractions, library preparation, Nucleic Acid Quality Control (QC), and NGS workflows
  • Conduct regular 1:1 meetings to deliver performance evaluations and guide career development
  • Directly execute sample processing alongside the team to maintain throughput
  • Serve as the primary technical point of contact, guiding data interpretation, next steps, and troubleshooting
  • Execute process development and method/instrument testing to increase operational precision and scale
  • Use data to identify lab process deviations, root-cause underlying issues, and document findings via nonconformance reports
  • Draft, generate, and review SOPs and work instructions
  • Maintain precise records using Google Sheets, Microsoft Excel, and LIMS
  • Ensure compliant management of samples with federal regulations
  • Collaborate with Oncology RUO peers to eliminate bottlenecks and optimize sample processing
  • Present data-backed summaries on team activities, milestones, and timelines
  • Adapt to evolving science and operational needs, taking ownership of tasks
  • Handle PHI in paper and electronic formats as required
  • Complete HIPAA/PHI privacy and security training within 30 days and maintain status

Qualifications

  • BS/BA in a biological science or equivalent
  • 3 to 4 years of related laboratory experience
  • Prior team management experience is highly preferred
  • Must pass a post-offer criminal background check

Skills

Required:Nucleic acid techniquesPipetting and lab automationNGS library preparation and platformsLIMS and data managementGoogle Workspace / Microsoft OfficeAnalytical thinking and data-driven troubleshootingCommunication and interpersonal skills
Nice to have:Leadership and team management

Benefits

  • Comprehensive health benefits (medical, dental, vision)
  • 401(k) with company match
  • Generous paid time off and company holidays
  • Additional wellness and work-life benefits
Last updated Oct 15, 2026. Interested? Apply on the company site.

About Natera

A global leader in cfDNA testing

Dedicated to oncology, women’s health, and organ health. Natera’s cell-free DNA tests help protect health and inform more personalized decisions about care.

oncologywomen's healthorgan healthcell-free DNA
Company profileWebsite

More open roles at Natera