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Staff Scientist R&D

Natera· Platform
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Hybrid (South San Francisco, CA)$157.3k - $196.6kFull-timePosted 2mo ago

About the role

Staff Scientist to lead and support assay development efforts in Natera's cfDNA lab, driving feasibility, development, verification and validation studies within a design control framework; mentors junior scientists and liaises across cross-functional teams.

Responsibilities

  • Lead technical projects and associated timelines and deliverables as a subject matter expert and represent the assay development group in cross-functional project teams.
  • Drive the planning, design, execution, and reporting of feasibility, development, verification and validation studies under the design control quality system.
  • Collaborate closely with research scientists, automation engineers, biostatisticians and data scientists within a dynamic R&D team to develop new and innovative molecular assays.
  • Communicate and document experimental data, scientific findings, and recommendations to R&D and other functions including Lab Operations, Scientific Affairs, Product Management, Quality, and Regulatory groups.
  • May manage Scientists or Research Associates.

Qualifications

  • BS, MS, or PhD in genetics, molecular biology, biochemistry or related field.
  • PhD with minimum 6 years relevant experience, or MS with minimum 8 years relevant experience.
  • Knowledge of high throughput NGS workflows or other genetic testing applications in clinical settings.
  • Experience in developing and validating molecular assays for CLIA lab testing.
  • Experience with automation of molecular workflows or assay transfer to automated platforms.
  • Experience in managing projects and direct reports.

Skills

Required:Long-range PCRLong-read sequencingNGS assay developmentqPCR, ddPCR, multiplex PCRAutomation of molecular workflowsData analysis (JMP, Excel, Python, R)Regulatory knowledgeCommunication

Benefits

  • Annual performance incentive bonus
  • Long-term equity awards
  • Comprehensive health benefits (medical, dental, vision)
  • 401(k) with company match
  • Generous paid time off and company holidays
  • Additional wellness and work-life benefits
Last updated Aug 27, 2026. Interested? Apply on the company site.

About Natera

A global leader in cfDNA testing

Dedicated to oncology, women’s health, and organ health. Natera’s cell-free DNA tests help protect health and inform more personalized decisions about care.

oncologywomen's healthorgan healthcell-free DNA
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