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Senior Scientist R&D

Natera· Platform
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Hybrid (South San Francisco)$138.1k - $172.6kFull-timePosted 2mo ago

About the role

Senior Scientist to join the assay development team in Natera’s cfDNA-focused R&D organization, leading and executing molecular assay development projects in a regulated environment, mentoring junior staff, and collaborating across functions to advance product portfolios.

Responsibilities

  • Lead technical projects and associated timelines and deliverables as a subject matter expert and represent the assay development group in cross-functional project teams.
  • Drive the planning, design, execution, and reporting of feasibility, development, verification and validation studies under the design control quality system.
  • Collaborate closely with research scientists, automation engineers, biostatisticians and data scientists within a dynamic R&D team to develop new and innovative molecular assays.
  • Communicate and document experimental data, scientific findings, and recommendations to R&D and other functions including Lab Operations, Scientific Affairs, Product Management, Quality, and Regulatory groups.
  • May manage Research Associates.

Qualifications

  • Typically requires a university degree and a minimum of 8+ years of related experience or a MS degree and 6 years of related experience or a PhD and 4 years of related experience
  • Knowledge of high throughput NGS workflows or other genetic testing applications in clinical settings.
  • Experience in developing and validating molecular assays for CLIA lab testing.
  • Experience with automation of molecular workflows or assay transfer to automated platforms.
  • Experience in managing projects.
  • Must possess very strong interpersonal, analytical, and problem-solving skills.

Skills

Required:NGS assay developmentqPCR, ddPCR, multiplex PCRAutomation / liquid handlingData analysis (JMP, Excel; Python, R)Regulatory knowledgeProject managementCommunication
Nice to have:Long-range PCR & long-read sequencing

Benefits

  • Annual performance incentive bonus
  • Long-term equity awards
  • Comprehensive health benefits (medical, dental, vision)
  • 401(k) with company match
  • Generous paid time off and company holidays
  • Additional wellness and work-life benefits
Last updated Aug 27, 2026. Interested? Apply on the company site.

About Natera

A global leader in cfDNA testing

Dedicated to oncology, women’s health, and organ health. Natera’s cell-free DNA tests help protect health and inform more personalized decisions about care.

oncologywomen's healthorgan healthcell-free DNA
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