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Senior/Lead Bioinformatics Scientist (Multi-Cancer Early Detection)

Natera· Molecular Biology Informatics & Statistics
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San Carlos, CA$131k - $180kFull-timePosted 1w ago

About the role

Senior or Lead Bioinformatics Scientist to join Natera’s Research team, developing and validating algorithms on large-scale multimodal genomic datasets to advance multi-cancer early detection from a single blood draw.

Responsibilities

  • Develop and validate new algorithms to analyze large multimodal epigenomic datasets
  • Drive research analyses through implementation, testing and performance evaluation, including developing new features within existing pipelines
  • Work with sequencing and clinical data from large cohorts, ensuring data integrity and quality control
  • Partner with molecular biologists and clinical scientists to solve challenging, open-ended problems
  • Visualize results and present complex findings to both technical and non-technical audiences
  • Contribute to the team’s standards for code quality and reproducibility

Qualifications

  • Ph.D. in Bioinformatics, Computer Science, Biology, or a related field; alternatively a Bachelor’s or Master’s degree with at least 4 years of professional experience
  • Track record developing and validating analysis workflows for high-throughput sequencing data
  • Experience applying and evaluating statistical and ML methods to large datasets
  • Strong quantitative reasoning and data analysis skills, applied effectively to real scientific problems.
  • Software development experience, including proficiency in Python and its scientific computing ecosystem
  • Fluent using Linux command-line tools and cloud computing environments
  • Strong verbal and written communication skills

Skills

Required:Bioinformatics analysis of high-throughput sequencing dataStatistical and machine learning methodsPython and scientific computingLinux and cloud computingCommunication

Benefits

  • Annual performance incentive bonus
  • Long-term equity awards
  • Comprehensive health benefits (medical, dental, vision)
  • 401(k) with company match
  • Generous paid time off and company holidays
  • Additional wellness and work-life benefits
Last updated Oct 15, 2026. Interested? Apply on the company site.

About Natera

A global leader in cfDNA testing

Dedicated to oncology, women’s health, and organ health. Natera’s cell-free DNA tests help protect health and inform more personalized decisions about care.

oncologywomen's healthorgan healthcell-free DNA
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