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Staff Machine Learning and Bioinformatics Scientist (Multi-Cancer Early Detection)

Natera· Molecular Biology Informatics & Statistics
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San Carlos, CA$169.8k - $212.3kFull-timePosted 1w ago

About the role

Staff ML and Bioinformatics Scientist to design models for multi-cancer early detection using large-scale multi-modal genomic data, collaborating with molecular biologists and clinical scientists to move methods from prototype to clinical validation.

Responsibilities

  • Lead the development of novel statistical and machine learning methods for cancer signal detection on multi-modal genomic data
  • Build interpretable, well-calibrated models, setting the standard for uncertainty estimation and reproducibility across the group
  • Prototype, test and productionize ML models using scalable infrastructure
  • Own key technical deliverables within larger projects and help shape the team’s research roadmap
  • Collaborate closely with molecular biologists and clinical experts on design and analysis of experiments and validation studies
  • Keep raising the bar through code and design reviews across projects
  • Translate complex results into clear stories for technical and non-technical audiences
  • Mentor junior scientists and champion a culture of curiosity, collaboration, and scientific excellence

Qualifications

  • PhD in Computer Science, Mathematics, Bioinformatics, or a related quantitative field with 6-12 years of experience post-PhD
  • Hands-on experience developing novel statistical / ML analysis methods applied to complex biological data
  • Proven track record of innovation and technical leadership in complex method development projects
  • Expertise in deep learning and multimodal foundation models
  • Proficient in Python and its scientific computing ecosystem
  • Scientific rigor throughout the R&D process, with eagerness to teach and learn new computational methods and biology
  • Excellent communication skills and a collaborative approach across teams

Skills

Required:PhD in quantitative fieldStatistical / ML analysis methodsDeep learning and multimodal foundation modelsPython and scientific computing ecosystemCommunication and collaboration
Nice to have:Biology data understanding

Benefits

  • Annual performance incentive bonus
  • Long-term equity awards
  • Comprehensive health benefits (medical, dental, vision)
  • 401(k) with company match
  • Generous paid time off and company holidays
  • Additional wellness and work-life benefits
Last updated Oct 15, 2026. Interested? Apply on the company site.

About Natera

A global leader in cfDNA testing

Dedicated to oncology, women’s health, and organ health. Natera’s cell-free DNA tests help protect health and inform more personalized decisions about care.

oncologywomen's healthorgan healthcell-free DNA
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