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Platform Engineering Lead | AI Infra

Plasmidsaurus· Engineering
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Hybrid (San Francisco)$205k - $235kFull-timePosted 5mo ago

About the role

Technical lead + manager for the compute, data, AI, and security infrastructure that runs our sequencing operation.

Responsibilities

  • Own core services that orchestrate lab devices (robots, sequencers, on-prem Linux servers) and the data ingestion pipeline
  • Build cloud infrastructure and data pipelines to house, process, and deliver terabytes of sequencing data
  • Design infrastructure to orchestrate millions of bioinformatics tasks (queues, workflow orchestration, scheduling)
  • Build AI infrastructure and internal tooling to enable agentic systems:
  • - Quality Scientist Agents - monitor operations end-to-end, surface anomalies, and intervene/escalate when quality or reliability issues appear
  • - Logistics Agents - coordinate drivers around the world to move packages to labs and carriers
  • - Bioinformatics Coding Agents - long-running agents for adaptive analysis of diverse sample types with unknown/shifting data distributions

Qualifications

  • BS in Computer Science, Computer Engineering, Math, Physics or technical subject
  • 7+ years of industry experience (or equivalent)
  • Prior experience leading projects and mentoring engineers (people or technical leadership)
  • Experience building LLM/agent systems (tooling, evaluation, safety/permissions, prompt + workflow design)
  • Primarily developing with coding agents in all parts of software lifecycle - design, implementation, test, review
  • Strong experience with REST API best practices (such as OpenAPI) and service-oriented architectures
  • Strong experience with SQL and data modeling in relational databases (postgres)
  • Strong experience with Python backend services (e.g., Flask/Django/FastAPI)
  • Strong experience working in AWS for containerized task orchestration (Lambda, ECS, Batch, StepFunctions)
  • Experience with infrastructure-as-code tools, like Terraform or AWS CDK
  • Experience building distributed systems with task queues (such as Celery and SQS)
  • Experience working with Linux servers (systemd services, basic networking, application deployment tools like ansible)
  • Comfort operating production systems: incident response, debugging, performance, reliability
  • Desire to learn about DNA sequencing bioinformatics algorithms and workflows

Skills

Required:Infrastructure orchestrationData pipeline designTask orchestration / queuesLLM / agent systems

Benefits

  • Equal opportunity employer
  • Careers email provided for accommodations
  • Opportunities to work on cutting-edge AI infrastructure in biotech
Last updated Aug 27, 2026. Interested? Apply on the company site.
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About Plasmidsaurus

Sequence Everything

Sequence everything.

RNA-SeqPlasmidsAmpliconsGenomesAAVMicrobiomeCustom
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