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Lead Security & Infrastructure Engineer

NewLimit· Predictive Modeling
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South San Francisco, CA$160k - $220kfull-timePosted 3mo ago

About the role

Lead IT, security, and infrastructure for NewLimit, owning systems, security, and data infrastructure as the company scales beyond 100 people. Hands-on IC with broad ownership, directing what to build, buy, automate, or outsource while coordinating with an MSP and vendors.

Responsibilities

  • Own identity, access, and endpoint standards across Google Workspace, AWS, GitHub, and macOS/Windows fleet: least privilege, phishing-resistant MFA, SSO, device compliance, and lifecycle automation.
  • Lead MSP and technical vendor relationships day to day: scope, SLAs, escalations, renewals, and performance. Help decide what we build, buy, outsource, or bring in-house.
  • Run security operations at scale, including monitoring, incident response, tabletop exercises, and post-incident reviews, working with MDR/IR partners where they add leverage.
  • Own network and office/lab infrastructure (connectivity, backups, continuity), and partner with the team on cloud and data infrastructure: AWS account structure and security and integrations between systems (lab instruments, HRIS, finance, ELN/LIMS).
  • Help build tooling and policies to scale: onboarding and access-review automation, security reporting, LLM/agent governance, data classification, software approval, and acceptable-use standards.

Qualifications

  • 4+ years in IT, infrastructure, or security, including experience as a primary or sole IT/security owner at a small company and managing MSPs or technical vendors.
  • Working fluency across identity, MDM, networking, AWS fundamentals, Google Workspace or M365 administration, backups, and SaaS administration.
  • You script well enough to automate your own work, move data between systems, and read someone else’s code.
  • Strong practical security judgment: right-size controls for company stage and changing expectations with sponsors, auditors, and regulated workflows.
  • You already use LLMs and agents to work more effectively, understand how to use them safely, and communicate clearly with scientists, executives, vendors, and auditors.

Skills

Required:Identity and Access ManagementVendor / MSP ManagementSecurity OperationsCloud and Data InfrastructureAutomation / Scripting

Benefits

  • Health, dental, and vision insurance
  • 401(k) with company match
  • Industry-leading paid time off (PTO), 20 days/year plus holidays
  • Paid parental leave
  • Meals and snacks on-site
Last updated Sep 17, 2026. Interested? Apply on the company site.

About NewLimit

Extending human healthspan

NewLimit is extending human healthspan by unlocking regenerative potential.

reprogrammingepigeneticsmedicineaginglongevity
Company profileWebsite

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