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Senior/Research Associate, mRNA Engineering

NewLimit· Technical Operations
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Hybrid (South San Francisco)$75k - $100kFull-timePosted 4d ago

About the role

Research-focused role developing and producing research-grade mRNA from DNA templates through IVT and purification, with documentation, collaboration across research and Delivery Sciences, and opportunities to contribute to protocol development in a fast-paced biotech environment.

Responsibilities

  • Execute established protocols for DNA template preparation, in vitro transcription, and downstream purification to generate research-grade mRNA
  • Run routine analytical assays to assess mRNA integrity and purity
  • Troubleshoot production issues and optimize yield, purity, and recovery under guidance of senior scientists
  • Maintain detailed records of experiments in Electronic Lab Notebooks
  • Follow and help maintain SOPs; contribute to drafting/updating protocols
  • Manage raw material and mRNA inventory, including sample tracking, storage, and reagent ordering
  • Maintain lab equipment and follow lab safety practices
  • Collaborate with Delivery Sciences and research teams to coordinate material needs and hand off mRNA for downstream studies
  • Present experiment results at team meetings

Qualifications

  • B.S. in Life Sciences, Chemistry, Engineering, or related field with 1-2 years of relevant full-time industry or academic research experience, or M.S. in Life Sciences
  • Hands-on experience with molecular biology techniques such as cloning, nucleic acid purification, PCR, and gel electrophoresis
  • Strong attention to detail and good documentation practices
  • Ability to execute protocols accurately and manage multiple tasks efficiently
  • Excellent communication and organizational skills
  • Interest in mRNA process science and eagerness to learn new techniques

Skills

Required:mRNA productionanalytical assays for mRNAdocumentationcollaboration

Benefits

  • Health, dental, and vision insurance
  • 401(k) with company match
  • Paid parental leave
  • Industry-leading paid time off (PTO) — 20 days/year for all employees + holidays
  • Meals and snacks on-site
Last updated Oct 22, 2026. Interested? Apply on the company site.

About NewLimit

Extending human healthspan

NewLimit is extending human healthspan by unlocking regenerative potential.

reprogrammingepigeneticsmedicineaginglongevity
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